1. Nchọpụta na mgbasa nke Omi Keron mutant strains Na Nọvemba 9, 2021, South Africa achọpụtala ụdị B.1.1.529 nke coronavirus ọhụrụ site na nlele ikpe maka oge mbụ.N'ime naanị izu 2, ụdị mutant ahụ ghọrọ ụdị ọrịa mutant kachasị ukwuu nke ọrịa ọrịa okpueze ọhụrụ na Gauteng Province, South Africa, na uto ya na-adị ngwa ngwa.Na Nọvemba 26, WHO kọwara ya dị ka “iche iche echiche” nke ise (VOC), nke akpọrọ mkpụrụedemede Greek Omicron (Omicron).Ka ọnwa Nọvemba 28, South Africa, Israel, Belgium, Italy, United Kingdom, Austria, na Hong Kong, China, enyochala ntinye nke ụdị mutant.A hụbeghị ntinye nke ụdị mutant a na mpaghara na obodo ndị ọzọ na obodo m.Achọpụtara mutant Omi Keron na mbụ na South Africa, mana ọ pụtaghị na nje a malitere na South Africa.Ebe a chọtara mutant abụghị isi ebe o si pụta.
2. Ihe nwere ike ime ka mpụta Omi Keron mutants dị ka ozi ugbu a na-ekesa ugbu a ọhụrụ okpueze nje nchekwa data GISAID, ọnụ ọgụgụ nke mutation saịtị nke ọhụrụ okpueze nje Omi Keron mutant nje bụ nke ukwuu karịa nke ọhụrụ okpueze nje. ụdị mutant nke na-ekesa n'ime afọ abụọ gara aga, ọkachasị na mmụgharị protein spike (Spike)..A na-eche na ihe kpatara mmalite ya nwere ike ịbụ ọnọdụ atọ ndị a: (1) Mgbe onye ọrịa ahụ na-arịa ọrịa immunodeficiency bu ọrịa coronavirus ọhụrụ ahụ, ọ nwetala ogologo oge nke evolushọn n'ime ahụ iji chịkọta ọnụ ọgụgụ dị ukwuu nke mmụgharị, bụ nke. na-ebufe site na ohere;(2) ụfọdụ anụmanụ na-efe efe New coronavirus, nje na-enweta mgbanwe mgbanwe n'oge mgbasa nke anụmanụ bi, na mmụgharị ọnụego dị elu karịa nke ụmụ mmadụ, wee wụsa n'ime mmadụ;(3) Ụdị mutant a na-aga n'ihu ruo ogologo oge na mba ma ọ bụ mpaghara ebe nleba anya ngbanwe nke genome coronavirus ọhụrụ na-adịte aka., N'ihi ezughị oke ike nlekota oru, nje virus nke etiti ọgbọ nke evolushọn enweghị ike ịhụ n'oge.
3. Ikike nnyefe nke Omi Keron mutant strain Ka ọ dị ugbu a, enweghị data nyocha usoro gbasara nnyefe, ọrịa nje na ikike mgbapụ nke ụmụ Omi Keron n'ụwa.Agbanyeghị, ụdị Omi Keron nwekwara saịtị mmụgharị amino acid dị mkpa na ụdị VOC anọ mbụ Alpha, Beta, Gamma na Delta spike protein, gụnyere ndị na-anabata cell emelitere.Saịtị mmụgharị maka mmekọrịta somatic na ike mmegharị nje.Ihe nleba anya gbasara ọrịa na ụlọ nyocha na-egosi na ọnụọgụ nke ụdị Omi Keron dị na South Africa abawanyela nke ukwuu, ma dochie akụkụ nke Delta (Delta).Ọ dị mkpa ka enyochakwu ikike nnyefe ma mụọ ya.
4. Mmetụta nke Omi Keron variant strain on vaccines and antibody drugs Studies egosiwo na ọnụnọ nke K417N, E484A, ma ọ bụ N501Y mutations na S protein nke ọhụrụ coronavirus na-egosi enwekwukwa dịghịzi mgbanaka ikike;ebe Omi Keron mutant nwekwara mmụgharị atọ nke "K417N+E484A+N501Y";na mgbakwunye, mutant Omi Keron nwekwara ọtụtụ mmụgharị ndị ọzọ nwere ike ibelata ọrụ nkwụsị nke ụfọdụ ọgwụ mgbochi monoclonal.Mgbanwe nke mmụgharị nwere ike ibelata nrụpụta nchebe nke ụfọdụ ọgwụ mgbochi megide ụmụ oke Omi Keron, yana ikike nke ọgwụ mgbochi dị ugbu a ịgbanarị ihe mgbochi chọrọ nyocha na nyocha ọzọ.
5. Ọdịiche Omi Keron ọ na-emetụta reagents nchọpụta nucleic acid eji ugbu a na obodo m?Nyocha genome nke ụdị mutant Omi Keron gosiri na saịtị mmụgharị ya anaghị emetụta nghọta na nkọwapụta nke isi ihe nchọpụta nucleic acid na obodo m.Saịtị mmụgharị nke ụdị mutant Omi Keron gbadoro ụkwụ na mpaghara mgbanwe dị ukwuu nke mkpụrụ ndụ protein S, na anọghị na mpaghara nchọpụta nucleic acid reagent primers na mpaghara nyocha nke ebipụtara na mbipụta nke asatọ nke mba m “New Coronavirus Pneumonia. Mmemme Mgbochi na Njikwa” (China The ORF1ab gene na N gene wepụtara nke erslọ Ọrụ Maka Nchịkwa na Mgbochi Ọrịa nye ụwa).Agbanyeghị, data sitere n'ọtụtụ ụlọ nyocha dị na South Africa na-egosi na reagents nchọpụta nucleic acid nke na-achọpụta mkpụrụ ndụ S nwere ike ọ gaghị enwe ike ịchọpụta mkpụrụ ndụ S nke ụdị Omi Keron nke ọma.
6. Usoro nke mba na mpaghara dị mkpa mere N'ihi ọrịa na-efe efe ngwa ngwa nke Omi Keron mutants na South Africa, ọtụtụ mba na mpaghara, gụnyere United States, United Kingdom, European Union, Russia, Israel, Taiwan obodo m na Taiwan. Hong Kong, amachibidola mbata nke ndị njem si ndịda Africa.
7. Nzaghachi nke obodo m na-atụ ihe mgbochi na njikwa nke obodo anyị nke "nchekwa mpụga, nchekwa ime ime megide nlọghachi" ka dị irè megide mutant Omi Keron.The Institute of Viral Diseases of China Center for Disease Control and Prevention ewepụtala usoro nchọpụta nucleic acid maka nje mutant nke Omi Keron, ma na-aga n'ihu na-eme nyocha genome nke nje maka ikpe enwere ike ibubata.Usoro ndị a kpọtụrụ aha n'elu ga-eme ka nchọpụta Omi Keron pụta n'oge nke enwere ike ibubata na obodo m.
8. Ndụmọdụ WHO maka ịzaghachi na ụdị mutant nke Omi Keron WHO na-atụ aro ka mba dị iche iche na-ewusi nyocha, mkpesa na nyocha nke coronavirus ọhụrụ, ma mee usoro ahụike ọha na eze dị irè iji kwụsị mgbasa nke nje;Usoro mgbochi ọrịa dị irè akwadoro maka ndị mmadụ n'otu n'otu gụnyere idobe anya ma ọ dịkarịa ala 1 mita n'ebe ọha na eze, iyi ihe mkpuchi, imeghe windo maka ikuku, na idobe Hichaa aka gị, ụkwara ma ọ bụ uzere n'ikpere ụkwụ gị ma ọ bụ anụ ahụ, gba ọgwụ mgbochi, wdg, na zere ịga ebe ikuku na-adịghị mma ma ọ bụ ebe ndị mmadụ juru.E jiri ya tụnyere ụdị VOC ndị ọzọ, ọ ka na-ejighị n'aka ma ụdị Omi Keron nwere nnyefe siri ike, ọrịa nje na ikike mgbanarị.Nnyocha dị mkpa ga-enweta nsonaazụ mbụ n'ime izu ole na ole na-abịa.Mana ihe a maara ugbu a bụ na ụdị mkpụrụ ndụ niile nwere ike ibute ọrịa siri ike ma ọ bụ ọnwụ, yabụ igbochi mgbasa nke nje bụ isi ihe mgbe niile, ọgwụ mgbochi okpueze ọhụrụ ka na-adịkwa irè n'ibelata ọrịa na ọnwụ siri ike.
9. N'ihu ụdị dị iche iche pụtara ọhụrụ nke coronavirus ọhụrụ Omi Keron, kedu ihe ọha mmadụ kwesịrị ịṅa ntị na ọrụ na ọrụ ha kwa ụbọchị?(1) Ikpuchi ihe mkpuchi ka bụ ụzọ dị mma isi gbochie mgbasa nke nje a, ọ dịkwa n'ụdị ụdị mutant Omi Keron.Ọbụlagodi na agwụla usoro ịgba ọgwụ mgbochi ọrịa na ịgba ọgwụ ike, ọ dịkwa mkpa iyi ihe mkpuchi n'ime ụlọ ọha, njem ọha na ebe ndị ọzọ.Na mgbakwunye, na-asa aka gị ugboro ugboro ma mee ka ikuku ikuku dị n'ime ụlọ ahụ.(2) Mee ezigbo ọrụ nke nlekota ahụike nke onwe.Mgbe enwere ihe mgbaàmà nke ndị a na-enyo enyo na oyi ịba ọhụrụ maka akwara obi, dị ka ahụ ọkụ, ụkwara, mkpụmkpụ ume na ihe mgbaàmà ndị ọzọ, na-enyocha ọnọdụ ahụ ozugbo wee bute ụzọ gaa hụ dọkịta.(3) Belata ntinye na ọpụpụ na-enweghị isi.N'ime ụbọchị ole na ole, ọtụtụ obodo na mpaghara akọpụtala n'ụzọ gara nke ọma mbubata ụdị mutant Omi Keron.China na-echekwa ihe ize ndụ nke ibubata ụdị mutant a, na ihe ọmụma zuru ụwa ọnụ ugbu a banyere ụdị mutant a ka nwere oke.Ya mere, ekwesịrị ibelata njem gaa n'ebe ndị nwere nnukwu ihe ize ndụ, na nchedo onwe onye mgbe ị na-eme njem kwesịrị ibelata ohere nke ibute ọrịa Omi Keron mutant.
Oge nzipu: Dec-17-2021